Lens parameters as predictors of intraocular pressure changes after phacoemulsification

Eye (Lond). 2015 Nov;29(11):1469-76. doi: 10.1038/eye.2015.141. Epub 2015 Jul 31.


Purpose: To evaluate intraocular pressure (IOP) change after cataract surgery in non-glaucomatous eyes with narrow and open angles (OAs) and its relation to novel lens parameters measured by anterior segment optical coherence tomography (AS-OCT).

Setting: University affiliated hospital, Farabi Eye Hospital, Tehran, Iran.

Design: Prospective interventional case series.

Methods: In this prospective study, 85 non-glaucomatous eyes underwent phacoemulsification and lens implantation. Thirty-nine eyes had OAs and 46 eyes had narrow angles (NAs). IOP and biometric parameters were measured by AS-OCT preoperatively and 3 months after surgery. Change in IOP and its relation to biometric parameters, including lens vault (LV), anterior vault (AV), defined as the sum of the LV and the ACD, and relative LV (rLV), defined as the ratio of the LV to the AV, were evaluated. The main outcome measure was degree of IOP change after phacoemulsification.

Results: Of the 85 patients included in the analysis, 35 were male and 50 were female with an overall mean age of 62.2 ± 8.9 years. The average IOP reduction was -4.95 ± 2.26 mm Hg, from a preoperative mean of 17.12 ± 2.47 mm Hg, at 3 months after cataract surgery. The amount of IOP reduction was significantly greater in the NA compared with the OA group. In multivariate linear regression analysis, preoperative IOP and AV were significantly associated with IOP decrease (all ≤ 0.03).

Conclusion: Cataract surgery results in IOP reduction in both OA and NA eyes. The amount of IOP reduction is related to AV.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anterior Chamber / anatomy & histology
  • Biometry
  • Female
  • Gonioscopy
  • Humans
  • Intraocular Pressure / physiology*
  • Lens Implantation, Intraocular*
  • Male
  • Middle Aged
  • Phacoemulsification*
  • Prospective Studies
  • Pseudophakia / physiopathology*
  • Tomography, Optical Coherence
  • Tonometry, Ocular
  • Trabecular Meshwork / anatomy & histology
  • Visual Acuity / physiology