PECAS: prokaryotic and eukaryotic classical analysis of secretome

Amino Acids. 2015 Dec;47(12):2659-63. doi: 10.1007/s00726-015-2058-2. Epub 2015 Aug 2.


Full sets of proteins that are transported to the extracellular space, called secretomes, have been studied for a variety of organisms to understand their potential role in crucial metabolic pathways and complex health conditions. However, there is a lack of tools for integrative classical analysis of secretomes that consider all the data sources available nowadays. Thus, PECAS (Prokaryotic and Eukaryotic Classical Analysis of Secretome) has been developed to provide a well-established prediction pipeline on secreted proteins for prokaryote and eukaryote species.

Keywords: Analysis pipeline; Bioinformatics; Prediction; Protein secretion; Secretome; Signal peptide.

MeSH terms

  • Algorithms
  • Animals
  • Bacterial Proteins / metabolism
  • Computational Biology
  • Eukaryota / metabolism*
  • False Positive Reactions
  • Humans
  • Internet
  • Metabolic Networks and Pathways
  • Protein Sorting Signals
  • Proteome / metabolism*
  • Proteomics / methods*
  • Species Specificity


  • Bacterial Proteins
  • Protein Sorting Signals
  • Proteome