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Review
. 2015 Jun;5(2):151-9.
doi: 10.15171/apb.2015.022. Epub 2015 Jun 15.

Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs

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Free PMC article
Review

Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs

Jafar Ezzati Nazhad Dolatabadi et al. Adv Pharm Bull. .
Free PMC article

Abstract

In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well as proteins and nucleic acids. Therefore, SLNs offer great promise for controlled and site specific drug and gene delivery. This article includes general information about SLN structures and properties, production procedures, characterization. In addition, recent progress on development of drug and gene delivery systems using SLNs was reviewed.

Keywords: Drug delivery; Gene delivery; Solid lipid nanoparticles; colloidal carrier.

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