Efficacy of antimicrobial property of two commercially available chemomechanical caries removal agents (Carisolv and Papacarie): An ex vivo study

J Int Soc Prev Community Dent. 2015 May-Jun;5(3):183-9. doi: 10.4103/2231-0762.159955.


Purpose: The purpose of the study is to evaluate the antimicrobial efficacy of Carisolv and Papacarie. There are only a few studies comparing the primary teeth. The objective of this study is to assess the effects of Carisolv and Papacarie on cariogenic flora and to compare them.

Materials and methods: Fifteen children aged 4-8 years who had at least two primary molars with broad occlusal cavitated lesions showing brown and softened dentin samples were selected. The selected 30 teeth were randomly divided into two groups of 15 teeth each for Carisolv and Papacarie. Dentin samples of both groups were taken prior to and following caries removal. The total viable count and lactobacilli count were determined and expressed as colony forming units per milliliter. The two methods of caries removal were then compared and the data were statistically analyzed.

Results: The data of both agents (groups) were analyzed by Wilcoxon signed-rank test before and after application and showed statistical significance. Inter-comparison of data of both groups was analyzed by Mann-Whitney U test for total viable count and total Lactobacillus count which showed no statistical significance.

Conclusion: Carisolv and Papacarie have similar antibacterial efficacy against cariogenic flora as chemomechanical caries removal agents.

Keywords: Carisolv; Papacarie; chemomechanical caries removal agents.