Natural History of Patent Ductus Arteriosus in Very Low Birth Weight Infants after Discharge

J Pediatr. 2015 Nov;167(5):1149-51. doi: 10.1016/j.jpeds.2015.06.032. Epub 2015 Aug 1.


Data on the natural history of infants discharged with patent ductus arteriosus is sparse. We report on the 36-months follow-up after hospitalization in 68 infants discharged with an open ductus arteriosus. Notwithstanding a high spontaneous closure rate, catheter intervention in 5 infants illustrates a critical need for cardiologic follow-up.

MeSH terms

  • Cardiac Catheterization*
  • Disease Progression
  • Ductus Arteriosus, Patent / diagnostic imaging
  • Ductus Arteriosus, Patent / therapy*
  • Echocardiography
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / therapy*
  • Infant, Very Low Birth Weight*
  • Male
  • Patient Discharge*
  • Prognosis
  • Retrospective Studies
  • Time Factors