Evaluation of Anterior Segment Parameters in Obesity

Korean J Ophthalmol. 2015 Aug;29(4):220-5. doi: 10.3341/kjo.2015.29.4.220. Epub 2015 Jul 21.


Purpose: To investigate anterior segment parameters in obese patients in comparison to healthy individuals.

Methods: Thirty-four obese subjects and 34 age-sex-matched healthy subjects were enrolled in this prospective cross-sectional study. Ophthalmological examinations including intraocular pressure (IOP), central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and axial length (AL) measurements were performed on each subject. Height and weight of all subjects were recorded and body mass index (BMI) was calculated.

Results: IOP was significantly higher in the obese group (p = 0.003). The mean ACD in obese subjects was significantly lower than that in control subjects (p = 0.036). AL, ACV, ACA and CCT were not significantly different between the groups. There was a positive correlation between BMI and IOP (r = 0.404, p < 0.001). ACD and ACA were negatively correlated with BMI.

Conclusions: IOP was significantly higher and ACD was significantly lower in obese subjects. AL, ACV, ACA and CCT were not significantly different between the groups. The impact of obesity on anterior chamber parameters should be further investigated.

Keywords: Anterior chamber parameters; Body mass index; Central corneal thickness; Intraocular pressure; Obesity.

MeSH terms

  • Adult
  • Aged
  • Anterior Chamber / pathology*
  • Anterior Chamber / physiopathology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Intraocular Pressure / physiology*
  • Male
  • Middle Aged
  • Obesity / diagnostic imaging*
  • Prospective Studies
  • Tomography, Optical Coherence / methods*
  • Tonometry, Ocular