Impaired renal excretion of hypoxanthine and xanthine in primary gout

Adv Exp Med Biol. 1989:253A:269-76. doi: 10.1007/978-1-4684-5673-8_45.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Gout / drug therapy
  • Gout / metabolism*
  • Humans
  • Hypoxanthine Phosphoribosyltransferase / metabolism
  • Hypoxanthines / blood
  • Hypoxanthines / pharmacokinetics*
  • Hypoxanthines / urine
  • Kidney / metabolism*
  • Kidney / pathology
  • Lesch-Nyhan Syndrome / metabolism
  • Male
  • Metabolic Clearance Rate
  • Middle Aged
  • Uric Acid / blood
  • Uric Acid / pharmacokinetics
  • Uric Acid / urine
  • Xanthines / blood
  • Xanthines / pharmacokinetics*
  • Xanthines / urine

Substances

  • Hypoxanthines
  • Xanthines
  • Uric Acid
  • Hypoxanthine Phosphoribosyltransferase