BioWardrobe: an integrated platform for analysis of epigenomics and transcriptomics data

Genome Biol. 2015 Aug 7;16(1):158. doi: 10.1186/s13059-015-0720-3.


High-throughput sequencing has revolutionized biology by enhancing our ability to perform genome-wide studies. However, due to lack of bioinformatics expertise, modern technologies are still beyond the capabilities of many laboratories. Herein, we present the BioWardrobe platform, which allows users to store, visualize and analyze epigenomics and transcriptomics data using a biologist-friendly web interface, without the need for programming expertise. Predefined pipelines allow users to download data, visualize results on a genome browser, calculate RPKMs (reads per kilobase per million) and identify peaks. Advanced capabilities include differential gene expression and binding analysis, and creation of average tag -density profiles and heatmaps. BioWardrobe can be found at .

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatin / metabolism
  • DNA-Binding Proteins / metabolism
  • Epigenomics / methods*
  • Gene Expression
  • Gene Expression Profiling / methods*
  • High-Throughput Nucleotide Sequencing
  • Histones / metabolism
  • Humans
  • Jumonji Domain-Containing Histone Demethylases / metabolism
  • Mice
  • Software*
  • T-Lymphocytes, Helper-Inducer / metabolism


  • Chromatin
  • DNA-Binding Proteins
  • Histones
  • Jumonji Domain-Containing Histone Demethylases
  • Kdm5b protein, mouse