Thermal detection of a prevascular tumor embedded in breast tissue

Math Biosci Eng. 2015 Oct;12(5):907-15. doi: 10.3934/mbe.2015.12.907.


This paper presents a mathematical model of heat transfer in a prevascular breast tumor. The model uses the steady state temperature of the breast at the skin surface to determine whether there is an underlying tumor and if so, verifies whether the tumor is growing or dormant. The model is governed by the Pennes equations and we present numerical simulations for versions of the model in two and three dimensions.

MeSH terms

  • Breast / pathology*
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / pathology*
  • Computer Simulation
  • Early Detection of Cancer / methods
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Models, Theoretical
  • Necrosis
  • Skin / pathology
  • Skin Temperature*
  • Software