Allopurinol Induced DRESS Syndrome

J Assoc Physicians India. 2014 Nov;62(11):63-5.

Abstract

A 45 years old female on allopurinol for 3 months presented with itching, rash, facial oedema and eosinophilia with hepatic and renal dysfunction. Skin biopsy revealed interface dermatitis, suggesting the diagnosis of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome.

Publication types

  • Case Reports

MeSH terms

  • Allopurinol / adverse effects*
  • Allopurinol / therapeutic use
  • Biopsy
  • Diagnosis, Differential
  • Drug Hypersensitivity Syndrome / diagnosis
  • Drug Hypersensitivity Syndrome / etiology*
  • Female
  • Gout Suppressants / adverse effects
  • Gout Suppressants / therapeutic use
  • Humans
  • Hyperuricemia / drug therapy
  • Middle Aged
  • Skin / pathology

Substances

  • Gout Suppressants
  • Allopurinol