Folliculotropic Mycosis Fungoides as a Posttransplant Lymphoproliferative Disorder

Pediatrics. 2015 Sep;136(3):e701-5. doi: 10.1542/peds.2014-3787. Epub 2015 Aug 17.

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is a known complication of solid organ transplantation. The majority are B cell in origin and related to Epstein-Barr virus infection. T-cell PTLD is much less common; most are Epstein-Barr virus negative and have a worse prognosis. Primary cutaneous T-cell lymphoma (CTCL) as a presentation of PTLD is rare. CTCL has a less favorable prognosis in transplant patients compared with that in immune-competent patients. Herein, we report a case of a 13-year-old boy who developed folliculotropic mycosis fungoides, a rare subtype of CTCL, subsequent to renal transplantation. To our knowledge, this is the first report of this type of PTLD in a pediatric patient.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects*
  • Kidney Transplantation / adverse effects*
  • Male
  • Mycosis Fungoides / etiology*
  • Mycosis Fungoides / therapy
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / therapy

Substances

  • Immunosuppressive Agents