Gut microbiota: Ganoderma lucidum, a new prebiotic agent to treat obesity?

Nat Rev Gastroenterol Hepatol. 2015 Oct;12(10):553-4. doi: 10.1038/nrgastro.2015.137. Epub 2015 Aug 18.


Modulation of the gut microbiota is one of the promising tools to tackle obesity. Chang and colleagues have recently shown that an extract of the mushroom Ganoderma lucidum, a traditional remedy in Asia, can reduce obesity in mice by modulating the gut microbiota, thereby exerting a prebiotic effect.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Drugs, Chinese Herbal / pharmacology*
  • Fungal Polysaccharides / pharmacology*
  • Gastrointestinal Microbiome / drug effects*
  • Insulin Resistance*
  • Obesity / microbiology*
  • Reishi*


  • Drugs, Chinese Herbal
  • Fungal Polysaccharides