Ebola Virus Disease: A Review of Its Past and Present

Anesth Analg. 2015 Sep;121(3):798-809. doi: 10.1213/ANE.0000000000000866.

Abstract

Ebola virus, the virus responsible for Ebola virus disease, has spawned several epidemics during the past 38 years. In 2014, an Ebola epidemic spread from Africa to other continents, becoming a pandemic. The virus's relatively unique structure, its infectivity and lethality, the difficulty in stopping its spread, and the lack of an effective treatment captured the world's attention. This article provides a brief review of the known history of Ebola virus disease, its etiology, epidemiology, and pathophysiology and a review of the limited information on managing patients with Ebola virus disease.

Publication types

  • Review

MeSH terms

  • Africa / epidemiology
  • Disease Outbreaks / prevention & control
  • Ebolavirus / isolation & purification*
  • Epidemics / prevention & control
  • Hemorrhagic Fever, Ebola / diagnosis*
  • Hemorrhagic Fever, Ebola / epidemiology*
  • Hemorrhagic Fever, Ebola / therapy
  • Humans