Pentazocine-induced Contractures: Dilemma in Management

Indian J Pharmacol. Jul-Aug 2015;47(4):451-3. doi: 10.4103/0253-7613.161276.


Pentazocine is a commonly used synthetic opioid analgesic for moderate to severe pain secondary to various conditions. Complications of parenteral opioid abuse including localized ulcerations, abscess, indurations, and sclerosis are well-documented. We present a rare case of drug abuse due to pentazocine (Fortwin) in a 32-year-old female, who had severe myogenic contractures of her knee joints.

Keywords: Contractures; myopathy; pentazocine; pentazocine abuse.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / adverse effects
  • Contracture / chemically induced*
  • Female
  • Humans
  • Injections, Intramuscular
  • Opioid-Related Disorders / complications*
  • Pentazocine / administration & dosage
  • Pentazocine / adverse effects*


  • Analgesics, Opioid
  • Pentazocine