EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision

Eur J Nucl Med Mol Imaging. 2015 Nov;42(12):1929-40. doi: 10.1007/s00259-015-3139-x. Epub 2015 Aug 21.


Since the publication of the European Association of Nuclear Medicine (EANM) procedural guidelines for radionuclide myocardial perfusion imaging (MPI) in 2005, many small and some larger steps of progress have been made, improving MPI procedures. In this paper, the major changes from the updated 2015 procedural guidelines are highlighted, focusing on the important changes related to new instrumentation with improved image information and the possibility to reduce radiation exposure, which is further discussed in relation to the recent developments of new International Commission on Radiological Protection (ICRP) models. Introduction of the selective coronary vasodilator regadenoson and the use of coronary CT-contrast agents for hybrid imaging with SPECT/CT angiography are other important areas for nuclear cardiology that were not included in the previous guidelines. A large number of minor changes have been described in more detail in the fully revised version available at the EANM home page: http://eanm.org/publications/guidelines/2015_07_EANM_FINAL_myocardial_perfusion_guideline.pdf .

Keywords: Guidelines; Myocardial perfusion imaging; Nuclear medicine; Procedures.

MeSH terms

  • Adult
  • Contrast Media
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / physiopathology
  • Dose-Response Relationship, Drug
  • Exercise
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Myocardial Perfusion Imaging / adverse effects
  • Myocardial Perfusion Imaging / instrumentation
  • Myocardial Perfusion Imaging / methods*
  • Practice Guidelines as Topic*
  • Purines / adverse effects
  • Purines / pharmacology
  • Pyrazoles / adverse effects
  • Pyrazoles / pharmacology
  • Radiation Exposure
  • Safety
  • Societies, Medical*
  • Software
  • Tomography, X-Ray Computed / adverse effects
  • Tomography, X-Ray Computed / instrumentation
  • Tomography, X-Ray Computed / methods*
  • Vasodilator Agents / adverse effects
  • Vasodilator Agents / pharmacology


  • Contrast Media
  • Purines
  • Pyrazoles
  • Vasodilator Agents
  • regadenoson