Vaccination of healthcare workers: A review

Hum Vaccin Immunother. 2015;11(11):2522-37. doi: 10.1080/21645515.2015.1082014.


Vaccine-preventable diseases are a significant cause of morbidity and mortality. As new vaccines are proving to be effective and as the incidence of some infections decreases, vaccination practices are changing. Healthcare workers (HCWs) are particularly exposed to and play a role in nosocomial transmission, which makes them an important target group for vaccination. Most vaccine-preventable diseases still carry a significant risk of resurgence and have caused outbreaks in recent years. While many professional societies favor vaccination of HCWs as well as the general population, recommendations differ from country to country. In turn, vaccination coverage varies widely for each microorganism and for each country, making hospitals and clinics vulnerable to outbreaks. Vaccine mandates and non-mandatory strategies are the subject of ongoing research and controversies. Optimal approaches to increase coverage and turn the healthcare workforce into an efficient barrier against infectious diseases are still being debated.

Keywords: coverage; healthcare worker; hepatitis; influenza; measles; mumps; nosocomial; pertussis; vaccination; varicella.

Publication types

  • Review

MeSH terms

  • Cross Infection / prevention & control*
  • Disease Transmission, Infectious / prevention & control*
  • Health Personnel*
  • Humans
  • Vaccination / statistics & numerical data
  • Vaccines / administration & dosage*
  • Vaccines / immunology*


  • Vaccines