Secular Trends of Gestational Diabetes Mellitus and Changes in Its Risk Factors

PLoS One. 2015 Aug 20;10(8):e0136017. doi: 10.1371/journal.pone.0136017. eCollection 2015.


Objective: The aim of this study was to evaluate the secular trends of incidence of gestational diabetes mellitus (GDM) and insulin treatment for GDM in a Korean population and to determine the factors that contribute to the trends in the incidence of GDM.

Study design: We used data collected by the Health Insurance Review & Assessment Service of Korea and analyzed data from women who had given birth from 2006 to 2010. We evaluated the trends in the incidence of GDM and GDM requiring insulin treatment and the changes in risk factors.

Results: There were 1,824,913 births during the study period, which included 129,666 cases of GDM, an incidence of 7.11% over this period. The incidence of GDM increased from 3.86% in 2007 to 11.83% in 2010, with a continuous increase after adjustment for age. However, the number of GDM cases that required insulin treatment decreased significantly from 13.87% in 2007 to 5.94% in 2010. The proportion of patients who were at an older age and multiparity, 2 GDM risk factors, increased during the study period.

Conclusions: In Korea, the incidence of GDM, especially mild GDM, increased dramatically during the period from 2006 to 2010. Further efforts are needed to monitor this trend and to identify associated factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Diabetes, Gestational / epidemiology*
  • Diabetes, Gestational / etiology
  • Female
  • Humans
  • Incidence
  • Parity
  • Pregnancy
  • Prevalence
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Young Adult

Grant support

This study was supported by a 2013-Grant from Korea Academy of Medical Sciences.