Ocular Adnexal Lymphomas: Single-Center Experience

Clin Lymphoma Myeloma Leuk. 2015 Jun;15 Suppl:S158-60. doi: 10.1016/j.clml.2015.02.015.


Ocular adnexal lymphoma (OAL) is a rare manifestation of non-Hodgkin lymphoma consisting of the tissues and structures surrounding the eye that include the conjunctiva, eyelids, lacrimal gland, and orbital soft tissues. OAL comprise 1% to 2% of all non-Hodgkin lymphomas and about 8% of the extranodal lymphomas; however, the incidence of OAL has increased by approximately 6% annually in last 2 decades, and OAL now represents the majority of orbital malignancies. There are no uniform treatment guidelines for OAL. Because of high local and extraorbital recurrence rates, appropriate local, systemic, or combined treatment must be applied.

Keywords: Conjunctiva; Eyelid; Lacrimal gland; Non-Hodgkin lymphoma; Ocular adnexa.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Eye Neoplasms / therapy*
  • Female
  • Humans
  • Lymphoma, Non-Hodgkin / complications*
  • Lymphoma, Non-Hodgkin / pathology
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies