Gastric Emptying of Liquids in Children

J Pediatr Gastroenterol Nutr. 2016 Mar;62(3):403-8. doi: 10.1097/MPG.0000000000000954.

Abstract

Objectives: The present study was performed to determine normal values for gastric half-emptying time (t1/2GE) of liquids in healthy children.

Methods: Gastric emptying (GE) of a standardized test milk-drink measured with technetium scintigraphy and the C-acetate breath test (C-ABT) was compared in 19 children ages between 4 and 15 years with upper gastrointestinal symptoms. The C-ABT was subsequently used to determine normal values for GE of the same liquid test meal in 133 healthy children ages between 1 and 17 years.

Results: In the group of children with upper gastrointestinal symptoms, the results showed a significant correlation (r = 0.604, P = 0.0006) between t1/2GE measured with both techniques. In the group of healthy children, the results of t1/2GE showed that there was no influence of age, sex, weight, height, and body mass index on GE.

Conclusions: Normal values for GE of a standardized test milk-drink in healthy children were determined with the C-ABT. This technique is considered reliable and is well accepted by the patients.

MeSH terms

  • Acetates
  • Adolescent
  • Animals
  • Breath Tests / methods*
  • Carbon Isotopes
  • Child
  • Child, Preschool
  • Female
  • Gastric Emptying / physiology*
  • Humans
  • Infant
  • Male
  • Meals
  • Milk
  • Radionuclide Imaging / methods
  • Reference Values
  • Stomach / diagnostic imaging
  • Stomach / physiology*
  • Technetium
  • Time Factors

Substances

  • Acetates
  • Carbon Isotopes
  • Technetium