A Modular Architecture for Electronic Health Record-Driven Phenotyping

AMIA Jt Summits Transl Sci Proc. 2015 Mar 25:2015:147-51. eCollection 2015.


Increasing interest in and experience with electronic health record (EHR)-driven phenotyping has yielded multiple challenges that are at present only partially addressed. Many solutions require the adoption of a single software platform, often with an additional cost of mapping existing patient and phenotypic data to multiple representations. We propose a set of guiding design principles and a modular software architecture to bridge the gap to a standardized phenotype representation, dissemination and execution. Ongoing development leveraging this proposed architecture has shown its ability to address existing limitations.