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Review
. 2015 Sep 1;7(9):a025064.
doi: 10.1101/cshperspect.a025064.

Comprehensive Catalog of Currently Documented Histone Modifications

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Free PMC article
Review

Comprehensive Catalog of Currently Documented Histone Modifications

Yingming Zhao et al. Cold Spring Harb Perspect Biol. .
Free PMC article

Abstract

Modern techniques in molecular biology, genomics, and mass spectrometry-based proteomics have identified a large number of novel histone posttranslational modifications (PTMs), many of whose functions are still under intense investigation. Here, we catalog histone PTMs under two classes: first, those whose functions have been fairly well studied and, second, those PTMs that have been more recently identified but whose functions remain unclear. We hope that this will be a useful resource for researchers from all biological or technical backgrounds, aiding in their chromatin and epigenetic pursuits.

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