An analysis of long-term results of treatment of 1258 patients with chronic lymphovenous insufficiency of lower extremities has shown the necessity of differentiated approach to different categories of the patients. A substantial improvement of results of the treatment of patients with complicated forms of varicose disease is observed in combination of operations on the venous and lymphatic systems. The character of these operations (lymphovenous anastomoses, lymphonodovenous anastomoses) must be determined strictly individually on the basis of an analysis of clinical course of the disease, data of lympho- and phlebography.