Healthy adult vaccination: An urgent need to prevent hepatitis B in China

Hum Vaccin Immunother. 2016 Mar 3;12(3):773-8. doi: 10.1080/21645515.2015.1086519.


Prevalence of hepatitis B is still high among adults in China, athough the prevalence in children has decreased dramatically. Immunization against hepatitis B among adults is urgently required. Through analyzing the immunogenicity of different doses, schedules and booster immunization among adults, we recommend 10 or 20 μg with a 0-1-6-month schedule or a 0-1-12-month schedule for migrant adults. For immunity failure, increasing the dose or covalent vaccine is suggested to provide protective antibodies. To enhance immunity among adults, hepatitis B vaccine should be included in health insurance.

Keywords: China; healthy adults; hepatitis B; immunization; prevalence.

Publication types

  • Review

MeSH terms

  • Adult
  • China / epidemiology
  • Health Policy
  • Hepatitis B / epidemiology*
  • Hepatitis B / prevention & control*
  • Hepatitis B Vaccines / administration & dosage*
  • Humans
  • Insurance, Health
  • Middle Aged
  • Prevalence
  • Vaccination / statistics & numerical data*


  • Hepatitis B Vaccines