A Method that Will Captivate U

Mol Cell. 2015 Sep 3;59(5):716-7. doi: 10.1016/j.molcel.2015.08.017.


In an age of next-generation sequencing, the ability to purify RNA transcripts has become a critical issue. In this issue, Duffy et al. (2015) improve on a pre-existing technique of RNA labeling and purification by 4-thiouridine tagging. By increasing the efficiency of RNA capture, this method will enhance the ability to study RNA dynamics, especially for transcripts normally inefficiently captured by previous methods.

Publication types

  • Comment

MeSH terms

  • Humans
  • MicroRNAs / chemistry*


  • MicroRNAs