Update on ventilator-associated pneumonia

Curr Opin Crit Care. 2015 Oct;21(5):430-8. doi: 10.1097/MCC.0000000000000231.

Abstract

Purpose of review: To highlight the importance of escalating pathogen resistance in ventilator-associated pneumonia (VAP) along with diagnostic and treatment implications.

Recent findings: In a period of rising bacterial resistance, VAP remains an important infection occurring in critically ill patients. Risk factors for multidrug-resistant pathogens depend on both local epidemiology and host factors. New diagnostic techniques and antimicrobials can help with rapid bacterial identification and timely and appropriate treatment while avoiding emergence of bacterial resistance.

Summary: Clinicians should be aware of risk factors for multidrug-resistant pathogens causing VAP and also of particularities of diagnosis and treatment of this important clinical entity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Critical Care / methods*
  • Critical Care / trends
  • Drug Resistance, Multiple, Bacterial / drug effects*
  • Guidelines as Topic
  • Humans
  • Immunocompromised Host / immunology
  • Intensive Care Units
  • Pneumonia, Ventilator-Associated / drug therapy
  • Pneumonia, Ventilator-Associated / immunology
  • Pneumonia, Ventilator-Associated / microbiology*
  • Pneumonia, Ventilator-Associated / prevention & control
  • Risk Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents