[Management of deep-vein thrombosis: A 2015 update]

J Mal Vasc. 2016 Feb;41(1):42-50. doi: 10.1016/j.jmv.2015.07.105. Epub 2015 Sep 8.
[Article in French]


Deep vein thrombosis (DVT) is a frequent and multifactor disease, with two major complications, post thrombotic syndrome and pulmonary embolism. Both transient (surgery, plaster immobilization, bed rest/hospitalization) and chronic/persistent (age, cancer, clinical or biological thrombophilia…) risk factors modulate treatment duration. Diagnostic management relies on clinical evaluations, probability followed by laboratory tests or imaging. So far, compression ultrasound is the diagnostic test of choice to make a positive diagnosis of DVT. Anticoagulants at therapeutic dose for at least 3 months constitute the cornerstones of proximal (i.e. involving popliteal or more proximal veins) DVT therapeutic management. The arrival of new oral anticoagulants should optimize ambulatory management of DVT.

Keywords: Anticoagulant; Deep vein thrombosis; Diagnosis; Diagnostic; Epidemiology; Thrombose veineuse profonde; Traitement; Treatment; Épidémiologie.

Publication types

  • Review

MeSH terms

  • Ambulatory Care
  • Anticoagulants / classification
  • Anticoagulants / therapeutic use
  • Combined Modality Therapy
  • Disease Management
  • Female
  • Fibrin Fibrinogen Degradation Products / analysis
  • Hospitalization
  • Humans
  • Immobilization
  • Male
  • Neoplasms / complications
  • Patient Education as Topic
  • Postthrombotic Syndrome / epidemiology
  • Postthrombotic Syndrome / etiology
  • Postthrombotic Syndrome / prevention & control
  • Pregnancy
  • Pregnancy Complications, Hematologic / therapy
  • Risk Factors
  • Stockings, Compression
  • Thrombectomy
  • Thrombophilia / complications
  • Thrombophilia / drug therapy
  • Ultrasonography, Doppler / methods
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / epidemiology
  • Venous Thrombosis / therapy*


  • Anticoagulants
  • Fibrin Fibrinogen Degradation Products
  • fibrin fragment D