[Treatment of the acute diverticulitis: A systematic review]

Presse Med. 2015 Nov;44(11):1113-25. doi: 10.1016/j.lpm.2015.08.004. Epub 2015 Sep 8.
[Article in French]


Acute diverticulitis is a common disease with increasing incidence. In most of cases, diagnosis is made at an uncomplicated stage offering a curative attempt under medical treatment and use of antibiotics. There is a risk of diverticulitis recurrence. Uncomplicated diverticulitis is opposed to complicated forms (perforation, abscess or fistula). Recent insights in the pathophysiology of diverticulitis, the natural history, and treatments have permitted to identify new treatment strategies. For example, the use of antibiotics tends to decrease; surgery is now less invasive, percutaneous drainage is preferred, peritoneal lavage is encouraged. Treatments of the diverticulitis are constantly evolving. In this review, we remind the pathophysiology and natural history, and summarize new recommendations for the medical and surgical treatment of acute diverticulitis.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Abscess / etiology
  • Abscess / surgery
  • Acute Disease
  • Age Factors
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Comorbidity
  • Dietary Fiber / therapeutic use
  • Disease Management
  • Disease Progression
  • Diverticulitis / complications
  • Diverticulitis / epidemiology
  • Diverticulitis / physiopathology
  • Diverticulitis / therapy*
  • Drainage / methods
  • Elective Surgical Procedures
  • Hospitalization
  • Humans
  • Intestinal Perforation / etiology
  • Laparoscopy
  • Multicenter Studies as Topic
  • Peritonitis / etiology
  • Probiotics / therapeutic use
  • Randomized Controlled Trials as Topic
  • Recurrence
  • Rifamycins / therapeutic use
  • Rifaximin
  • Therapeutic Irrigation


  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Dietary Fiber
  • Rifamycins
  • Rifaximin