Abstract
A 57-year-old woman diagnosed with ectopic Cushing syndrome was found to have a 111In-octreotide-avid corticotropin-producing pancreatic neuroendocrine tumor with liver metastases. She was treated with 4 induction and 4 maintenance cycles of 177Lu-DOTATATE, which normalized her serum corticotropin levels and dramatically reduced the size of the pancreatic primary and liver metastases.
MeSH terms
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Adrenocorticotropic Hormone / biosynthesis*
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Female
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Humans
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Liver Neoplasms / secondary
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Middle Aged
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Neuroendocrine Tumors / metabolism*
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Neuroendocrine Tumors / pathology
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Neuroendocrine Tumors / radiotherapy*
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Octreotide / analogs & derivatives*
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Octreotide / therapeutic use
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Organometallic Compounds / therapeutic use*
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Pancreatic Neoplasms / metabolism*
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Pancreatic Neoplasms / pathology
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Pancreatic Neoplasms / radiotherapy*
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Receptors, Peptide / metabolism*
Substances
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Organometallic Compounds
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Receptors, Peptide
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Adrenocorticotropic Hormone
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lutetium Lu 177 dotatate
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Octreotide