A case of relapsing-remitting tumour-like inflammation of the central nervous system

Mult Scler. 2015 Nov;21(13):1742-5. doi: 10.1177/1352458515599076. Epub 2015 Sep 11.

Abstract

The case of a 37-year-old woman suffering from a relapsing-remitting tumefactive inflammatory disease of the central nervous system (CNS) is described. The patient had four severe relapses over eight years, and was treated with steroids, immunosuppression and plasma-exchange with modest benefit. No magnetic resonance imaging or cerebrospinal spinal fluid findings suggestive of multiple sclerosis emerged during the eight-year follow-up. 'Relapsing-remitting tumefactive inflammation' seems to have the features of a distinct inflammatory CNS disease.

Keywords: Tumour-like lesions; central nervous system; inflammation; multiple sclerosis; relapsing–remitting.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology*
  • Brain Neoplasms / cerebrospinal fluid
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / pathology*
  • Demyelinating Diseases / cerebrospinal fluid
  • Demyelinating Diseases / drug therapy
  • Demyelinating Diseases / pathology*
  • Encephalitis / cerebrospinal fluid
  • Encephalitis / drug therapy
  • Encephalitis / pathology*
  • Female
  • Glucocorticoids / therapeutic use
  • Hemianopsia / cerebrospinal fluid
  • Hemianopsia / drug therapy
  • Hemianopsia / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Methylprednisolone / therapeutic use
  • Recurrence
  • Syndrome

Substances

  • Glucocorticoids
  • Methylprednisolone