Influence of Sex on Suicidal Phenotypes in Affective Disorder Patients with Traumatic Childhood Experiences

PLoS One. 2015 Sep 14;10(9):e0137763. doi: 10.1371/journal.pone.0137763. eCollection 2015.

Abstract

Objectives: In the current study, we aimed to investigate the impact of childhood trauma on suicidal behaviour phenotypes in a group of patients with diagnosed affective disorder (unipolar or bipolar affective disorder).

Patients and methods: Patients with and without a history of childhood abuse, measured by Childhood Trauma Questionnaire (CTQ), were assessed to explore risks for suicidal behaviour (including suicide attempt, self-harm and non-suicidal self-injury). The tested sample consisted of 258 patients (111 males and 147 females, in-patients and out-patients at the Department of Psychiatry and Psychotherapy, Medical University of Vienna and University Hospital Tulln, Lower Austria). Psychiatric diagnoses were derived from the SCAN (Schedules for Clinical Assessment in Neuropsychiatry) interview. In addition, patients were administered the Lifetime Parasuicidal Count (LPC), Suicidal Behaviour Questionnaire (SBQ-R), and Viennese Suicide Risk Assessment Scale (VISURIAS) questionnaires.

Results: In contrast to male suicide attempters, female suicide attempters showed both significantly higher total CTQ scores (p<0.001), and higher CTQ subscores (emotional, physical and sexual abuse, as well as emotional and physical neglect) in comparison to the non-suicidal control group. Besides, females with a history of self-harming behaviour (including suicidal intention) and Non-Suicidal-Self Injury (NSSI) had significantly higher CTQ total scores (p<0.001) than the control group.

Conclusion: These findings suggest gender differences in suicidal behaviour after being exposed to childhood trauma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Adult Survivors of Child Abuse / psychology*
  • Adult Survivors of Child Abuse / statistics & numerical data
  • Aged
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mood Disorders / psychology*
  • Personality Assessment
  • Personality Inventory
  • Sex Factors
  • Suicide / psychology*
  • Suicide / statistics & numerical data
  • Young Adult

Grants and funding

This work was supported by the Austrian Science Fund (FWF)—Grant Number KLI°220 (by AS), www.fwf.ac.at. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.