First assessment of short-term efficacy of Er:YAG laser treatment on stress urinary incontinence in women: prospective cohort study

Climacteric. 2015;18 Suppl 1:37-42. doi: 10.3109/13697137.2015.1071126.


Objectives: This is the first assessment of efficacy and safety of the Er:YAG laser in the treatment of stress urinary incontinence. The aim of this study was to assess the short-term outcome of a non-invasive laser treatment for mild-to-severe stages of this condition and to check its applicability in different body mass index and age groups.

Methods: A prospective cohort, single-center study at the Ob/Gyn Clinic, Zagreb, Croatia recruited a consecutive sample of 73 female patients suffering from stress urinary incontinence. The procedure was performed with a 2940-nm Er:YAG laser (XS Dynamis, Fotona, Slovenia) designed to achieve heating up of vaginal mucosa to around 60°C, 500-700 μm in depth.

Results: The score in the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form was reduced to a median of 46% (95% confidence interval 33-67%; p < 0.001). The reduction was significantly higher in women with normal body mass index (67%) than in overweight women (25%), as well as in women younger than 39 years (100%) compared with those older than 60 years (8%) (p < 0.001). No serious adverse events were noticed.

Conclusion: This study of Er:YAG laser therapy in women has demonstrated a clinically relevant, short-term improvement of stress urinary incontinence, with minimal adverse events of a transient nature.


MeSH terms

  • Adult
  • Age Factors
  • Body Mass Index
  • Cohort Studies
  • Croatia
  • Female
  • Humans
  • Hyperthermia, Induced / methods
  • Lasers, Solid-State / therapeutic use*
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome
  • Urinary Incontinence, Stress / therapy*