Troponin elevation after noncardiac surgery: Significance and management

Cleve Clin J Med. 2015 Sep;82(9):595-602. doi: 10.3949/ccjm.82a.15076.


How to interpret and manage troponin elevations after noncardiac surgery is a common clinical question for cardiologists and internists. An estimated 5% to 25% of patients who undergo noncardiac surgery have an elevated postoperative troponin level. Patients with troponin elevation are at higher short-term and long-term risk of morbidity and mortality. Current guidelines provide few recommendations on how to manage these patients. The authors review the evidence and guidelines and propose treatment strategies.

Trial registration: NCT02291419.

Publication types

  • Review

MeSH terms

  • Biomarkers / blood
  • Early Diagnosis
  • Humans
  • Myocardial Infarction* / blood
  • Myocardial Infarction* / diagnosis
  • Myocardial Infarction* / etiology
  • Postoperative Complications* / blood
  • Postoperative Complications* / diagnosis
  • Practice Guidelines as Topic
  • Risk Assessment
  • Surgical Procedures, Operative / adverse effects*
  • Troponin / blood*


  • Biomarkers
  • Troponin

Associated data