Abstract
Gold nanoparticles (AuNPs) have been chemically functionalized onto multiwalled carbon nanotubes (MWCNT) through a metallopolymer linker-bis (2,2':6'2"-terpyridine) ruthenium(II)-connected diblock poly(N-isopropyacryamide). A "nano-snowflower" pattern was formed by self-assembly MWCNT-AuNP nanocomposite with anti-DNP IgE antibody. MWCNT-AuNP nanohybrid has unique biocompatibility and electronic current-voltage properties. This nanohybrid shows the potential application for IgE biosensor to diagnose cancer cells. We represent a step towards building complex electronic circuits response by providing molecular recognition properties.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Adsorption
-
Antibodies, Monoclonal / chemistry
-
Antibodies, Monoclonal / immunology*
-
Conductometry / instrumentation
-
Electric Conductivity
-
Equipment Design
-
Equipment Failure Analysis
-
Gold / chemistry*
-
Immunoassay / instrumentation*
-
Immunoglobulin E / analysis
-
Immunoglobulin E / immunology*
-
Materials Testing
-
Metal Nanoparticles / chemistry*
-
Nanocomposites / chemistry
-
Nanocomposites / ultrastructure
-
Particle Size
-
Protein Binding
-
Ruthenium / chemistry*
-
Surface Properties
Substances
-
Antibodies, Monoclonal
-
Immunoglobulin E
-
Gold
-
Ruthenium