Detection of novel kobu-like viruses in Japanese black cattle in Japan

J Vet Med Sci. 2016 Feb;78(2):321-4. doi: 10.1292/jvms.15-0447. Epub 2015 Sep 11.


During surveillance for bovine diarrhea of unknown causes in Japanese black cattle in Kagoshima Prefecture, Japan, we found two types of novel kobu-like viruses in fecal samples of calves. Sequence analyses revealed that they had L protein and 2A protein with H-box/NC sequence motif, which are present in kobuviruses. Phylogenetic analysis revealed that they were related to kobuviruses; however, they clustered apart from other kobuviruses. In the prevalence study of two types of novel kobu-like viruses, 16.9% and 10.4% prevalence of these viruses were observed in the feces of diarrheal calves in this area.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / epidemiology
  • Cattle Diseases / virology*
  • Diarrhea / veterinary
  • Diarrhea / virology
  • Feces / virology
  • Japan / epidemiology
  • Kobuvirus / classification
  • Kobuvirus / isolation & purification*
  • Phylogeny
  • Picornaviridae Infections / epidemiology
  • Picornaviridae Infections / veterinary*
  • Picornaviridae Infections / virology
  • Prevalence