Normal Gain of VOR with Refixation Saccades in Patients with Unilateral Vestibulopathy

J Int Adv Otol. 2015 Aug;11(2):133-7. doi: 10.5152/iao.2015.1087.


Objective: To characterize the response in the video head-impulse test for the assessment of the vestibulo-ocular reflex (VOR) in patients because of vertigo and dizziness.

Materials and methods: After rightward and leftward head impulses, the following results evaluated were: gain of the reflex and appearance of refixation saccades. A particular type of response (normal gain VOR and refixation saccades) was evaluated in a group of patients.

Results: In patients with a unilateral abnormality consisting of normal gain and refixation saccades, there was a close concordance with the diseased side and the side to which head impulses elicited the abnormal result.

Conclusion: In the assessment of patients with dizziness, finding a normal gain VOR with refixation saccades indicates the existence of a peripheral vestibulopathy and localizes to the side of the lesion.

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Dizziness* / etiology
  • Dizziness* / physiopathology
  • Female
  • Head Impulse Test / methods
  • Head Movements / physiology
  • Humans
  • Male
  • Middle Aged
  • Reflex, Vestibulo-Ocular*
  • Reproducibility of Results
  • Saccades / physiology
  • Vertigo* / etiology
  • Vertigo* / physiopathology
  • Vestibular Diseases* / complications
  • Vestibular Diseases* / diagnosis
  • Vestibular Diseases* / physiopathology