A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force

Bipolar Disord. 2015 Nov;17(7):689-704. doi: 10.1111/bdi.12331. Epub 2015 Sep 19.


Objectives: In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD).

Methods: This task force report addresses the unique aspects of OABD including epidemiology and clinical features, neuropathology and biomarkers, physical health, cognition, and care approaches.

Results: The report describes an expert consensus summary on OABD that is intended to advance the care of patients, and shed light on issues of relevance to BD research across the lifespan. Although there is still a dearth of research and health efforts focused on older adults with BD, emerging data have brought some answers, innovative questions, and novel perspectives related to the notion of late onset, medical comorbidity, and the vexing issue of cognitive impairment and decline.

Conclusions: Improving our understanding of the biological, clinical, and social underpinnings relevant to OABD is an indispensable step in building a complete map of BD across the lifespan.

Keywords: bipolar disorder; cognition; elderly; geriatric; manic depressive disorder; mood stabilizers.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Age of Onset
  • Aged
  • Bipolar Disorder* / drug therapy
  • Bipolar Disorder* / epidemiology
  • Bipolar Disorder* / physiopathology
  • Bipolar Disorder* / psychology
  • Cognition*
  • Comorbidity
  • Female
  • Geriatric Assessment
  • Humans
  • Male
  • Psychotropic Drugs / therapeutic use*


  • Psychotropic Drugs