Tackling reproducibility in academic preclinical drug discovery

Nat Rev Drug Discov. 2015 Nov;14(11):733-4. doi: 10.1038/nrd4737. Epub 2015 Sep 21.

Abstract

The reproducibility of biomedical research on novel drug targets has become suspect. Here, we highlight how drug discovery centres embedded in academic institutions, but with a translational imperative, can help address this reproducibility crisis.

MeSH terms

  • Academic Medical Centers / methods
  • Academic Medical Centers / standards*
  • Animals
  • Biomedical Research / methods
  • Biomedical Research / standards*
  • Drug Discovery / methods
  • Drug Discovery / standards*
  • Drug Evaluation, Preclinical / methods
  • Drug Evaluation, Preclinical / standards*
  • Humans
  • Reproducibility of Results
  • Translational Medical Research / methods
  • Translational Medical Research / standards