Atypical Features of Fuchs Uveitis Syndrome

Optom Vis Sci. 2015 Nov;92(11):e394-403. doi: 10.1097/OPX.0000000000000701.


Purpose: To review the atypical features of Fuchs uveitis syndrome.

Methods: A retrospective review of records of a private optometric practice of patients with diagnosed Fuchs uveitis syndrome was performed.

Results: Three atypical cases of Fuchs uveitis syndrome are presented. Patient 1 is a patient who required the use of topical corticosteroids to alleviate acute symptoms of uveitis. Patient 2 is a patient who presented at a very young age with aggressive Fuchs uveitis and who subsequently developed secondary open-angle glaucoma. Patient 3 presented with primary open-angle glaucoma, was treated with topical ocular hypotensive medications, but then subsequently presented with manifest Fuchs uveitis syndrome in the affected eye. Patient 3 was treated with topical prostaglandin analogs among other medical therapies.

Conclusions: Fuchs uveitis syndrome has a diverse clinical spectrum. It is a syndrome that is diagnosed using a constellation of clinical signs. However, some cases may present atypically and clinicians should be prepared to use less conventional therapies such as topical corticosteroids and prostaglandin analogs in the treatment of acute uveitic attacks and secondary open-angle glaucoma, respectively.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use
  • Female
  • Glaucoma, Open-Angle / diagnosis
  • Glaucoma, Open-Angle / drug therapy
  • Glucocorticoids / therapeutic use
  • Humans
  • Intraocular Pressure
  • Iridocyclitis / diagnosis*
  • Iridocyclitis / drug therapy
  • Male
  • Ocular Hypertension / diagnosis
  • Ocular Hypertension / drug therapy
  • Retrospective Studies
  • Young Adult


  • Antihypertensive Agents
  • Glucocorticoids