Approximately independent linkage disequilibrium blocks in human populations

Bioinformatics. 2016 Jan 15;32(2):283-5. doi: 10.1093/bioinformatics/btv546. Epub 2015 Sep 22.


We present a method to identify approximately independent blocks of linkage disequilibrium in the human genome. These blocks enable automated analysis of multiple genome-wide association studies.

Availability and implementation: code:; data:


Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Chromosome Mapping / methods*
  • Genetic Markers
  • Genome, Human*
  • Genome-Wide Association Study*
  • Humans
  • Linkage Disequilibrium
  • Software*


  • Genetic Markers