Thymic non-lymphoid cells cultured for transplantation purposes. Immunostimulatory effect on ataxia telangiectasia peripheral blood mononuclear cells

Arch Immunol Ther Exp (Warsz). 1989;37(3-4):471-80.


The analysis of various methods of thymic non-lymphoid cells (TNLC) culture in vitro was performed. The TNLC obtained in culture of small thymic fragments in Eagle's minimal essential medium with 30% of fetal calf serum have been found to be biologically active as indicated by their ability to enhance proliferative activity and Il-2 production of peripheral blood mononuclear cells derived from ataxia telangiectasia patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ataxia / immunology*
  • Biological Factors / metabolism
  • Biological Factors / pharmacology*
  • Cell Division / drug effects
  • Cells, Cultured
  • Child
  • Culture Media / pharmacology
  • Humans
  • Leukocytes, Mononuclear / cytology*
  • Leukocytes, Mononuclear / drug effects
  • Thymus Gland / cytology*
  • Thymus Gland / metabolism


  • Biological Factors
  • Culture Media