Age-Stratified Prevalence of Mild Cognitive Impairment and Dementia in European Populations: A Systematic Review

J Alzheimers Dis. 2015;48(2):355-9. doi: 10.3233/JAD-150168.


The prevalence of mild cognitive impairment (MCI) and dementia according to age remain uncertain. We systematically extracted age-stratified estimates of MCI and dementia prevalence reported in European studies published since 1995, and performed meta-analyses for dementia. We identified 10 relevant studies on MCI and 26 studies on dementia. Studies on MCI presented substantial heterogeneity preventing a meta-analysis, with a majority reporting an increase in prevalence at ≥75 years old. Pooled prevalence of dementia rose continuously from 55 years of age, reaching 44.7% (39.8; 49.6) in those ≥95 years of age. Homogenization of MCI criteria, and additional studies in Northern European population would be warranted.

Keywords: Dementia; epidemiology; mild cognitive impairment; prevalence.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Age Factors
  • Cognitive Dysfunction / epidemiology*
  • Dementia / epidemiology*
  • Europe / epidemiology
  • Humans
  • Prevalence