Idarucizumab, a Specific Dabigatran Reversal Agent, Reduces Blood Loss in a Porcine Model of Trauma With Dabigatran Anticoagulation

J Am Coll Cardiol. 2015 Sep 29;66(13):1518-9. doi: 10.1016/j.jacc.2015.07.051.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Humanized / pharmacology
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Anticoagulants / adverse effects*
  • Blood Coagulation / drug effects*
  • Blood Coagulation / physiology
  • Dabigatran / adverse effects*
  • Hemorrhage / chemically induced*
  • Hemorrhage / drug therapy*
  • Hemorrhage / pathology
  • Humans
  • Male
  • Swine

Substances

  • Antibodies, Monoclonal, Humanized
  • Anticoagulants
  • idarucizumab
  • Dabigatran