First Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis

H Detering; T Aebischer; P W Dabrowski; A Radonić; A Nitsche; B Y Renard; A F Kiderlen

doi:10.1128/genomeA.01013-15

First Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis

Genome Announc. 2015 Sep 24;3(5):e01013-15. doi: 10.1128/genomeA.01013-15.

Authors

H Detering¹, T Aebischer², P W Dabrowski³, A Radonić⁴, A Nitsche⁴, B Y Renard⁵, A F Kiderlen⁶

Affiliations

¹ Research Group Bioinformatics (NG4), Robert Koch Institute, Berlin, Germany Division for Mycotic, Parasitic and Mycobacterial Diseases (FG16), Robert Koch Institute, Berlin, Germany.
² Division for Mycotic, Parasitic and Mycobacterial Diseases (FG16), Robert Koch Institute, Berlin, Germany.
³ Research Group Bioinformatics (NG4), Robert Koch Institute, Berlin, Germany Centre for Biological Threats and Special Pathogens (ZBS1), Robert Koch Institute, Berlin, Germany.
⁴ Centre for Biological Threats and Special Pathogens (ZBS1), Robert Koch Institute, Berlin, Germany.
⁵ Research Group Bioinformatics (NG4), Robert Koch Institute, Berlin, Germany.
⁶ Division for Mycotic, Parasitic and Mycobacterial Diseases (FG16), Robert Koch Institute, Berlin, Germany kiderlena@rki.de.

Abstract

The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 isolate cultured from the brain of a deceased mandrill baboon.