Morgan's Legacy: Fruit Flies and the Functional Annotation of Conserved Genes

Cell. 2015 Sep 24;163(1):12-4. doi: 10.1016/j.cell.2015.09.009.

Abstract

In 1915, "The Mechanism of Mendelian Heredity" was published by four prominent Drosophila geneticists. They discovered that genes form linkage groups on chromosomes inherited in a Mendelian fashion and laid the genetic foundation that promoted Drosophila as a model organism. Flies continue to offer great opportunities, including studies in the field of functional genomics.

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Drosophila melanogaster / genetics*
  • Genetic Techniques
  • Genetics / history*
  • History, 20th Century
  • Humans
  • Models, Animal