Abstract
Phytoetrogens and vitamin D administered in a dose-dependent manner effectively prevents bone loss in postmenopausal women and reduces the incidence of fractures. Recently, genistein has been found to stimulate the production of osteoprotegerin by human paracrine osteoblasts, providing a further mechanism for the bone-sparing effects of isoflavones.
MeSH terms
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Bone and Bones / drug effects
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Bone and Bones / pathology
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Female
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Genistein / therapeutic use
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Humans
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Osteoporosis, Postmenopausal / epidemiology
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Osteoporosis, Postmenopausal / pathology
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Osteoporosis, Postmenopausal / prevention & control*
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Phytoestrogens / therapeutic use*
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Vitamin D / therapeutic use*
Substances
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Phytoestrogens
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Vitamin D
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Genistein