[Relationship between serum zinc levels and attention deficit hyperactivity disorder in children]

Zhongguo Dang Dai Er Ke Za Zhi. 2015 Sep;17(9):980-3.
[Article in Chinese]

Abstract

Objective: To study the possible relationship between serum zinc levels and attention deficit hyperactivity disorder (ADHD) in Chinese children.

Methods: Following a systematic search for case-control studies on the serum zinc levels in Chinese children with ADHD published between 2000 and 2015, a Meta analysis was conducted using Stata 12.0 software.

Results: A total of 17 studies, including 2 177 children with ADHD and 2 900 normal children, were enrolled. The Meta analysis showed that serum zinc levels in children with ADHD were lower than normal children (SMD= -1.33; 95%CI: -2.22, -0.44; P=0.003). The sensitivity analysis indicated that the results were reliable. Eggerγs test did not find the existence of publication bias.

Conclusions: Serum zinc levels may be associated with susceptibility to ADHD in children.

Publication types

  • English Abstract
  • Meta-Analysis
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / blood
  • Case-Control Studies
  • Child
  • Humans
  • Zinc / blood*

Substances

  • Zinc