Evaluation of Nutritional Status of Patients with Depression

Biomed Res Int. 2015;2015:521481. doi: 10.1155/2015/521481. Epub 2015 Aug 27.


Aims and objectives: Our goal was to determine nutritional status, body composition, and biochemical parameters of patients diagnosed with depression based on DSM-IV-TR criteria.

Methods: A total of 59 individuals, aged 18-60 years admitted to Mental Health Centre of Kayseri Education and Research Hospital, were included in the study. The participants were randomly assigned to two groups; depression group (n = 29) and control group (n = 30). Anthropometric measurements, some biochemical parameters, demographic data, and 24-hour dietary recall were evaluated.

Results: 65.5% of depression and 60.0% of control group were female. Intake of vitamins A, thiamine, riboflavin, B6, folate, C, Na, K, Mg, Ca, P, Fe, Zn, and fibre (p < 0.05) were lower in depression group. Median levels of body weight, waist circumference, hip circumference, waist-to-hip ratio (p < 0.05) were significantly higher in depression group. Fasting blood glucose levels, serum vitamins B12, and folic acid (p < 0.05) in depression group were lower than controls. Serum insulin and HOMA levels of two groups were similar.

Conclusion: Some vitamin B consumption and serum vitamin B12 and folic acid levels were low while signs of abdominal obesity were high among patients with depression. Future research exploring nutritional status of individuals with depression is warranted.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Body Mass Index
  • Case-Control Studies
  • Depression / blood
  • Depression / metabolism*
  • Diet
  • Female
  • Folic Acid / blood
  • Humans
  • Male
  • Middle Aged
  • Nutritional Status
  • Vitamin B 12 / blood
  • Young Adult


  • Blood Glucose
  • Folic Acid
  • Vitamin B 12