Medication use and potentially inappropriate medications in those with limited prognosis living in residential aged care

Australas J Ageing. 2016 Jun;35(2):E18-24. doi: 10.1111/ajag.12220. Epub 2015 Sep 28.

Abstract

Aim: To compare the prevalence in residential aged care (RAC) of preventative and potentially inappropriate medications (PIMs) in those who died within 12 months versus those alive after 12 months.

Methods: Firstly, a cross-sectional survey of 6196 people living in RAC in Auckland. Secondly, a research physician searched electronic hospital records in one District Health Board for a sub-sample (n = 222) of these residents. Classes of medications and dates of death were obtained from the Ministry of Health databases. Those who died versus those alive at 12 months were compared.

Results: Over half of the 6196 participants received antihypertensives and/or antiplatelet agents. Cardiovascular preventative medications were significantly more common in those who died within 12 months. Seventy percent in high-level care received psychotropics. PIMs were commonly used.

Conclusions: Use of preventative medications is common in RAC, especially during the last year of life. Psychotropics are very commonly used, despite being potentially inappropriate.

Keywords: frail elderly; homes for the aged; inappropriate prescribing; palliative care; polypharmacy.

MeSH terms

  • Age Factors
  • Aged, 80 and over
  • Cardiovascular Agents / adverse effects
  • Cardiovascular Agents / therapeutic use*
  • Comorbidity
  • Cross-Sectional Studies
  • Drug Utilization Review
  • Electronic Health Records
  • Female
  • Frail Elderly
  • Health Care Surveys
  • Homes for the Aged*
  • Humans
  • Inappropriate Prescribing* / prevention & control
  • Life Expectancy
  • Male
  • New Zealand
  • Nursing Homes
  • Polypharmacy
  • Potentially Inappropriate Medication List*
  • Preventive Health Services / methods*
  • Prognosis
  • Psychotropic Drugs / adverse effects
  • Psychotropic Drugs / therapeutic use*
  • Retrospective Studies
  • Risk Factors
  • Time Factors

Substances

  • Cardiovascular Agents
  • Psychotropic Drugs