Lymphocytic choriomeningitis virus infection induced by percutaneous exposure

O Aebischer; P Meylan; S Kunz; C Lazor-Blanchet

doi:10.1093/occmed/kqv156

Lymphocytic choriomeningitis virus infection induced by percutaneous exposure

Occup Med (Lond). 2016 Mar;66(2):171-3. doi: 10.1093/occmed/kqv156. Epub 2015 Sep 28.

Authors

O Aebischer¹, P Meylan², S Kunz³, C Lazor-Blanchet⁴

Affiliations

¹ Department of Internal Medicine, CHUV, 1011 Lausanne, Switzerland, oriane.aebischer@chuv.ch.
² Department of Infectious Disease, CHUV, 1011 Lausanne, Switzerland.
³ Department of Microbiology, CHUV, 1011 Lausanne, Switzerland.
⁴ Department of Preventive and Occupational Medicine, CHUV, 1011 Lausanne, Switzerland.

PMID: 26416845
DOI: 10.1093/occmed/kqv156

Abstract

We report a case of acquired lymphocytic choriomeningitis virus (LCMV) infection due to an accidental percutaneous inoculation of LCMV at work. The injured worker developed a flu-like syndrome, followed by pericarditis and meningoencephalitis. Seroconversion was confirmed by ELISA. The patient made a complete recovery. We review measures undertaken to prevent a similar event and propose a follow-up protocol in the event of accidental LCMV exposure.

Keywords: Accidents; laboratory workers; needlestick injuries..

Publication types

Case Reports

MeSH terms

Accidents, Occupational*
Adult
Antiviral Agents / administration & dosage*
Humans
Lymphocytic Choriomeningitis / drug therapy*
Lymphocytic Choriomeningitis / etiology
Lymphocytic Choriomeningitis / virology
Lymphocytic choriomeningitis virus / pathogenicity*
Male
Needlestick Injuries / virology*
Occupational Exposure / adverse effects*
Post-Exposure Prophylaxis
Practice Guidelines as Topic
Ribavirin / administration & dosage*
Treatment Outcome

Substances

Antiviral Agents
Ribavirin