Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control?

Dent Clin North Am. 2015 Oct;59(4):799-829. doi: 10.1016/j.cden.2015.06.002.


Also note that structured abstracts are not allowed per journal style: What is the effect of a mouthwash containing various active chemical ingredients on plaque control and managing gingivitis in adults based on evidence gathered from existing systematic reviews? The summarized evidence suggests that mouthwashes containing chlorhexidine(CHX) and essential oils (EO) had a large effect supported by a strong body of evidence. Also there was strong evidence for a moderate effect of cetylpyridinium chloride(CPC). Evidence suggests that a CHX mouthwash is the first choice, the most reliable alternative is EO. No difference between CHX and EO with respect to gingivitis was observed.

Keywords: Dental plaque; Gingivitis; Meta-review; Mouthrinse; Mouthwash; Systematic review.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Anti-Infective Agents, Local / therapeutic use*
  • Dental Plaque / drug therapy*
  • Gingivitis / drug therapy*
  • Humans
  • Mouthwashes / therapeutic use*
  • Oral Health


  • Anti-Infective Agents, Local
  • Mouthwashes